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작성일 2013-12-01 조회수 2256
파일첨부 Granovsky and Yarnitsky - 2013-CPM.PDF
제목
[MEDOC]Personalized Pain Medicine
Personalized Pain Medicine:
The Clinical Value of Psychophysical Assessment of Pain Modulation Profile


Yelena Granovsky. Ph.D.* and David Yarnitsky. M.D. Department of Neurology. Rambam Medical Center. and Clinical Neurophysiology Lab. Faculty of Medicine. Technion ? Israel Institute of Technology. Haifa. Israel


ABSTRACT
Experimental pain stimuli can be used to simulate patients’ pain experience. We review recent developments in psychophysical pain testing. focusing on the application of the dynamic tests?conditioned pain modulation (CPM) and temporal summation (TS). Typically. patients with clinical pain of various types express either less efficient CPM or enhanced TS. or both. These tests can be used in prediction of incidence of acquiring pain and of its intensity. as well as in assisting the correct choice of analgesic agents for individual patients. This can help to shorten the commonly occurring long and frustrating process of adjusting analgesic agents to the individual patients. We propose that evaluating pain modulation can serve as a step forward in individualizing pain medicine.
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